Dimethyl-SGD-1882
Dimethyl-SGD-1882 is a potent DNA alkylating agent derived from a pyrrolobenzodiazepine (PBD) dimer. It functions as a cytotoxic payload in antibody-drug conjugates (ADCs), disrupting DNA replication in target cells. Its mechanism is studied in both in vitro cytotoxicity assays and in vivo xenograft models for oncology research.
Product Specifications
CAS Number
3026416-27-0
Smiles
C[C@@]12N (C (C3=CC (OC) =C (OCCCOC4=C (C=C5C (N=C[C@]6 (C) N (C=C (C7=CC=C (OC) C=C7) C6) C5=O) =C4) OC) C=C3N=C2) =O) C=C (C8=CC=C (N) C=C8) C1
Molecular Formula
C44H43N5O7
Molecular Weight
753.84
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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