Ezetimibe ketone
Ezetimibe ketone (EZM-K), an active metabolite of Ezetimibe, exhibits antioxidant properties by reducing H2O2-induced ROS and apoptosis in renal NRK-52E cells through the upregulation of the Nrf2/HO-1 pathway. This small molecule is a valuable research tool for investigating oxidative stress mechanisms in vitro and exploring potential nephroprotective applications.
Product Specifications
CAS Number
191330-56-0
Product Name Alternative
EZM-K, Ezetimibe ketone, NPC1L1, Nrf2
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery
Purity
99.32% (May vary between batches)
Solubility
DMSO:80 mg/mL (196.36 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.91 mM)
Smiles
C (CC (=O) C1=CC=C (F) C=C1) [C@@H]2[C@H] (N (C2=O) C3=CC=C (F) C=C3) C4=CC=C (O) C=C4
Molecular Formula
C24H19F2NO3
Molecular Weight
407.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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