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Ibrutinib dimer

Ibrutinib dimer is an impurity formed by the dimerization of Ibrutinib, a potent and irreversible Bruton's tyrosine kinase (Btk) inhibitor with an IC50 of 0.5 nM. This small molecule is widely used in biochemical and cellular research to investigate Btk signaling in oncology and autoimmune disease models, both in vitro and in vivo.

Product Specifications

CAS Number

2031255-23-7

Field of Research

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Smiles

N (CCC (=O) N1C[C@@] (CCC1) (N2C=3C (C (=N2) C4=CC=C (OC5=CC=CC=C5) C=C4) =C (N) N=CN3) [H]) C6=C7C (N (N=C7C8=CC=C (OC9=CC=CC=C9) C=C8) [C@]%10 (CN (C (C=C) =O) CCC%10) [H]) =NC=N6

Molecular Formula

C50H48N12O4

Molecular Weight

880.99

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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