INY-03-041
INY-03-041 is a potent, pan-AKT PROTAC degrader, conjugating GDC-0068 to lenalidomide to selectively degrade AKT1/2/3. It demonstrates low nanomolar IC50 values and is a valuable chemical tool for studying AKT signaling in cancer research, applicable in both cellular and in vivo models.
Product Specifications
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
O=C (C (N (CC1=C2C=CC=C1CCCCCCCCCCNC[C@H] (C3=CC=C (Cl) C=C3) C (N4CCN (C5=C ([C@H] (C) C[C@H]6O) C6=NC=N5) CC4) =O) C2=O) CC7) NC7=O
Molecular Formula
C44H56ClN7O5
Molecular Weight
798.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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