O-Desmethyl apixaban
O-Desmethyl apixaban, the primary active metabolite of Apixaban, is a potent and reversible direct Factor Xa inhibitor. It demonstrates high selectivity with Ki values of 0.08 nM (human) and 0.17 nM (rabbit) . This compound is a valuable pharmacological tool for studying anticoagulant mechanisms in both biochemical and pharmacokinetic research models.
Product Specifications
CAS Number
503612-76-8
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
O=C (N) C1=NN (C2=CC=C (O) C=C2) C=3C (=O) N (C4=CC=C (C=C4) N5C (=O) CCCC5) CCC13
Molecular Formula
C24H23N5O4
Molecular Weight
445.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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