Kushenol K
Kushenol K, a flavonoid antioxidant isolated from the roots of Sophora flavescens. Kushenol K is a cytochrome P-450 3A4 (CYP3A4) inhibitor with a Ki value of 1.35 μM[1]. Kushenol K shows weak antiviral activity against HSV-2 (EC50 of 147 μM) [2]. Kushenol K also inhibits the activity of SGLT1 and SGLT2[3].
Product Specifications
CAS Number
101236-49-1
UNSPSC
12352005
Target
Cytochrome P450; HSV; SGLT
Type
Natural Products
Related Pathways
Anti-infection; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Infection; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/kushenol-k.html
Solubility
10 mM in DMSO
Smiles
COC(C=C1O)=C(C2=O)C(O[C@H](C(C=CC(O)=C3)=C3O)[C@@H]2O)=C1C[C@H](C(C)=C)CCC(C)(O)C
Molecular Formula
C26H32O8
Molecular Weight
472.53
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
CYP3; HSV-2; SGLT1; SGLT2
Frequently Asked Questions
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