Luteolin 7-sulfate

Luteolin 7-sulfate is isolated from Phyllospadix iwatensis Makino, a marine plant. Luteolin 7-sulfate attenuates TYR gene expression through the intervention of a cAMP-responsive element binding protein (CREB) - and microphthalmia-associated transcription factor (MITF) -mediated signaling pathway, leading to the decreased melanin synthesis[1].

Product Specifications

CAS Number

[56857-57-9]

UNSPSC

12352005

Target

Epigenetic Reader Domain

Type

Natural Products

Related Pathways

Epigenetics

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/luteolin-7-sulfate.html

Purity

95.0

Solubility

DMSO : 62.5 mg/mL (ultrasonic)

Smiles

O=C1C2=C(O)C=C(OS(=O)(O)=O)C=C2OC(C3=CC(O)=C(O)C=C3)=C1

Molecular Formula

C15H10O9S

Molecular Weight

366.30

References & Citations

[1]Lee SW, et al. Luteolin 7-Sulfate Attenuates Melanin Synthesis through Inhibition of CREB- and MITF-Mediated Tyrosinase Expression. Antioxidants (Basel) . 2019 Apr 4;8 (4) .