Tyrosinase-IN-29
Tyrosinase-IN-29 (compound 5c) is a potent inhibitor of tyrosinase abTYR (IC50: 6.11 μM) . Tyrosinase-IN-29 can be used to further study the inhibition of skin hyperpigmentation[1].
Product Specifications
CAS Number
408335-66-0
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Tyrosinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/tyrosinase-in-29.html
Smiles
CC1=CC2=C(C=C1)NC(=O)C(=C2)O
Molecular Formula
C10H9NO2
Molecular Weight
175.18
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Jacobs ME, Petzer JP, Pretorius J, Cloete SJ, Crous C, Petzer A. Synthesis and evaluation of 3-hydroxyquinolin-2 (1H) -one derivatives as inhibitors of tyrosinase. Bioorg Med Chem Lett. 2024 May 31;109:129823.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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