LY290324
LY290324 is a potent and orally active leukotriene D4 (LTD4) antagonist. LY290324 reduces LTC4, LTD4 and LTE4 (HY-113465) -induced bronchospasm. LY290324 has the potential for the research of antigen-induced bronchospasm[1].
Product Specifications
CAS Number
[146554-87-2]
UNSPSC
12352005
Target
Leukotriene Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ly290324.html
Smiles
ClC1=CC=C2C=CC(/C=C/C3=CC=CC(CN4C=CC5=C4C(CCC6=NN=NN6)=CC=C5)=C3)=NC2=C1.[H]Cl
Molecular Formula
C29H23ClN6.xHCl
References & Citations
[1]Boot JR, et al. The pharmacology of LY290324 in the guinea-pig: an orally active, potent and selective cysteinyl leukotriene receptor antagonist. Eur J Pharmacol. 1993 Jan 26;231 (1) :83-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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