LY290324

LY290324 is a potent and orally active leukotriene D4 (LTD4) antagonist. LY290324 reduces LTC4, LTD4 and LTE4 (HY-113465) -induced bronchospasm. LY290324 has the potential for the research of antigen-induced bronchospasm[1].

Product Specifications

CAS Number

[146554-87-2]

UNSPSC

12352005

Target

Leukotriene Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ly290324.html

Smiles

ClC1=CC=C2C=CC(/C=C/C3=CC=CC(CN4C=CC5=C4C(CCC6=NN=NN6)=CC=C5)=C3)=NC2=C1.[H]Cl

Molecular Formula

C29H23ClN6.xHCl

References & Citations

[1]Boot JR, et al. The pharmacology of LY290324 in the guinea-pig: an orally active, potent and selective cysteinyl leukotriene receptor antagonist. Eur J Pharmacol. 1993 Jan 26;231 (1) :83-9.