PROTAC CDK2/9 Degrader-1
PROTAC CDK2/9 Degrader-1 is a bifunctional molecule that potently induces the degradation of both CDK2 and CDK9, with half-maximal degradation concentrations (DC50) of 62 nM and 33 nM, respectively. This compound serves as a valuable chemical probe for investigating cell cycle regulation and transcription in cancer research, applicable for both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2408641-24-5
Field of Research
Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery
Smiles
O=C (NC1=CC=C (C=C1) CN2CCN (C (=O) CCC (=O) NCCNC3=CC=CC=4C (=O) N (C (=O) C34) C5C (=O) NC (=O) CC5) CC2) C6=NNC=C6NC=7N=CN=C8NC=CC87
Molecular Formula
C40H41N13O7
Molecular Weight
815.84
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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