PROTAC EED degrader-1
PROTAC EED degrader-1 is a potent, heterobifunctional molecule that targets the EED subunit of the PRC2 complex for degradation, exhibiting high binding affinity (pKD 9.02) and functional inhibition (pIC50 8.17) . It serves as a valuable chemical probe for studying PRC2 biology and epigenetics in both cellular and in vivo research contexts.
Product Specifications
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Smiles
FC1=CC=C2C (CCO2) =C1CNC3=NC=C (C4=C (C) N=C (CCC (NCCOC5=CC=C (OCC (N[C@@H] (C (C) (C) C) C (N6[C@H] (C (NCC7=CC=C (C8=C (C) N=CS8) C=C7) =O) C[C@@H] (O) C6) =O) =O) C=C5) =O) C=C4) C9=NN=CN39
Molecular Formula
C55H60FN11O8S
Molecular Weight
1054.2
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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