E3 ubiquitin ligase binder-1
E3 ubiquitin ligase binder-1 (compound 11) is a potent E3 ubiquitin ligase binder. E3 ubiquitin ligase binder-1 is a ligand for E3 Ligase[1].
Product Specifications
CAS Number
[2446913-99-9]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e3-ubiquitin-ligase-binder-1.html
Solubility
10 mM in DMSO
Smiles
O=C1NC(CCN1C2=CC=C(C3CCNCC3)C=C2)=O.[H]Cl
Molecular Formula
C15H20ClN3O2
Molecular Weight
309.79
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Andrew J. P, et, al. Targeted protein degradation. WO2020132561A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
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