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Emilumenib

Emilumenib (Menin-MLL inhibitor 26) is an orally active Menin-MLL inhibitor. Emilumenib also is an active reference. Emilumenib can inhibits cell growth. Emilumenib can be used for the research of leukemia[1].

Product Specifications

CAS Number

2440018-29-9

Product Name Alternative

DS-1594a; Menin-MLL inhibitor 26

UNSPSC

12352005

Target

Epigenetic Reader Domain

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/emilumenib.html

Purity

96.22

Solubility

DMSO : 41.67 mg/mL (ultrasonic; warming)

Smiles

CN([C@H]1C[C@H](C[C@H]1O)NCC2=CC=C(C3=CC(OC)=C(N=N3)OC)C=C2)C4=C5C(SC(CC(F)(F)F)=C5)=NC=N4

Molecular Formula

C27H29F3N6O3S

Molecular Weight

574.62

References & Citations

[1]Cycloalkane-1, 3-diamine derivatives, et al. Cycloalkane-1, 3-diamine derivatives. Patent. CN113164481A.|[2]Numata M, et al., A novel Menin-MLL1 inhibitor, DS-1594a, prevents the progression of acute leukemia with rearranged MLL1 or mutated NPM1. Cancer Cell Int. 2023 Feb 25;23 (1) :36.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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