Peruvoside

Peruvoside is a cardiac glycoside that acts as a Na+/K+-ATPase inhibitor and a Src kinase inhibitor. It enhances myocardial contractility and exhibits anticancer activity by inducing cell cycle arrest and apoptosis via MAPK, Wnt/β-catenin, and PI3K/AKT/mTOR pathways in leukemia and NSCLC models, as demonstrated in in vitro studies.

Product Specifications

CAS Number

1182-87-2

Product Name Alternative

Encordin

Field of Research

Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Purity

98.96% (May vary between batches)

Solubility

DMSO:200 mg/mL (364.52 mM)

Smiles

C (=O) [C@@]12[C@@]3 ([C@] ([C@]4 (O) [C@] (C) (CC3) [C@H] (CC4) C=5COC (=O) C5) (CC[C@@]1 (C[C@@H] (O[C@H]6[C@@H] (O) [C@H] (OC) [C@@H] (O) [C@H] (C) O6) CC2) [H]) [H]) [H]