NMS-0963
NMS-0963 is a potent, orally bioavailable SYK inhibitor with an IC50 of 3 nM. It demonstrates anti-proliferative activity in BaF3-TEL/SYK cells (IC50=27 nM), supporting its use in researching SYK-dependent pathways in immunology and oncology, both in vitro and in vivo.
Product Specifications
CAS Number
2765304-82-1
Field of Research
Cardiovascular Research, Neuroscience, Signal Transduction
Smiles
C (N[C@H] (CN1CCC1) C) (=O) C2=CC (=NN2C) C3=NC (NC4=CC (OC) =CC (OC) =C4) =NC=C3
Molecular Formula
C23H29N7O3
Molecular Weight
451.52
Storage Conditions
-20°C
Notes
For research use only.
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