NP3-562
NP3-562 is a potent, orally bioavailable tricyclic NLRP3 inflammasome inhibitor with an IC50 of 214 nM. In vivo, oral administration (30 mg/kg) significantly reduces IL-1β levels in a murine acute peritonitis model, supporting its utility for researching NLRP3-driven pathologies.
Product Specifications
CAS Number
2409825-32-5
Field of Research
Immunology & Inflammation
Smiles
C (C) (C) (O) C=1N2C3=C (C=C2C (=O) N (CC (N[C@H]4CN (C) CCC4) =O) N1) SC (Cl) =C3
Molecular Formula
C19H24ClN5O3S
Molecular Weight
437.94
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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