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OICR-8268

OICR-8268 is a potent, reversible DCAF1 WDR domain binder (Kd = 38 nM) used to develop DCAF1-directed PROTAC degraders. It serves as a critical chemical probe for targeted protein degradation research in both cellular and in vivo models.

Product Specifications

CAS Number

3000549-26-5

Field of Research

Pharmacology & Drug Discovery

Smiles

C (N[C@@H] (CC (N) =O) C1=CC (Cl) =C (F) C=C1) (=O) C=2C (=NNC2) C3=C (F) C=C (Cl) C=C3

Molecular Formula

C19H14Cl2F2N4O2

Molecular Weight

439.24

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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