OICR-8268
OICR-8268 is a potent, reversible DCAF1 WDR domain binder (Kd = 38 nM) used to develop DCAF1-directed PROTAC degraders. It serves as a critical chemical probe for targeted protein degradation research in both cellular and in vivo models.
Product Specifications
CAS Number
3000549-26-5
Field of Research
Pharmacology & Drug Discovery
Smiles
C (N[C@@H] (CC (N) =O) C1=CC (Cl) =C (F) C=C1) (=O) C=2C (=NNC2) C3=C (F) C=C (Cl) C=C3
Molecular Formula
C19H14Cl2F2N4O2
Molecular Weight
439.24
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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