PARP1/c-Met-IN-1
PARP1/c-Met-IN-1 (Compound 16) is a potent dual inhibitor of PARP1 and c-Met with IC50 values of 3.3 nM and 32.2 nM, respectively. It induces apoptosis and G2/M phase arrest in MDA-MB-231 cells and demonstrates significant in vivo antitumor efficacy in mouse models, supporting oncology and cancer signaling pathway research.
Product Specifications
CAS Number
2944101-99-7
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology, Signal Transduction
Smiles
O (CCN1N=C (C=CC1=O) C=2C=CC=NC2) C=3C4=C (C=C (C=C4) N5CCN (C (=O) C6=CC (CC=7C=8C (C (=O) NN7) =CC=CC8) =CC=C6F) CC5) N=CC3
Molecular Formula
C40H33FN8O4
Molecular Weight
708.74
Storage Conditions
-20°C
Notes
For research use only.
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