PARP7-IN-18
Parp7-in-18 (Compound 8) is a potent and selective PARP7 inhibitor exhibiting sub-nanomolar inhibitory activity (IC50 = 0.11 nM) . This compound demonstrates promising antitumor efficacy in cellular assays and favorable pharmacokinetic profiles in preclinical models, supporting its use in oncology research targeting PARP7-dependent pathways.
Product Specifications
CAS Number
2819999-00-1
Field of Research
Epigenetics & Chromatin, Molecular Biology, Signal Transduction
Smiles
C (OCCC (=O) N1C[C@]2 (N (CC1) C=3C (OCC2) =CC (Cl) =CN3) [H]) [C@H]4N (CC4) C5=C (C (F) (F) F) C (=O) NN=C5
Molecular Formula
C23H26ClF3N6O4
Molecular Weight
542.94
Storage Conditions
-20°C
Notes
For research use only.
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