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PDE1-IN-6

PDE1-IN-6 (6c) is a potent and selective PDE1 inhibitor with an IC50 of 7.5 nM. It demonstrates anti-leukemic activity by suppressing proliferation and promoting apoptosis in acute myelogenous leukemia (AML) cell lines in vitro, supporting its use in oncology and signal transduction research.

Product Specifications

CAS Number

2877017-16-6

Field of Research

Cell Biology, Metabolism Research

Smiles

C (C) (C) (C) N1C2=C (C (=O) N (CC3=CC (F) =CC=C3) C (NCCNC4=CC=C (F) C=C4) =N2) C=N1

Molecular Formula

C24H26F2N6O

Molecular Weight

452.50

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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