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PfFAS-II inhibitor 1

PfFAS-II Inhibitor 1 (Compound 3) is a potent and selective inhibitor of the Plasmodium falciparum FabI enzyme (IC50 = 0.63 μM), which is essential for the parasite's fatty acid biosynthesis. This small molecule is a valuable chemical tool for investigating the FAS-II pathway in malaria parasites through both in vitro enzymatic assays and in vivo antimalarial studies.

Product Specifications

CAS Number

1459704-68-7

Field of Research

Infectious Disease & Virology, Pharmacology & Drug Discovery

Smiles

O (C=1C=C2C (OC (=O) C=C2) =CC1) C3=C (O) C=C (Cl) C=C3

Molecular Formula

C15H9ClO4

Molecular Weight

288.68

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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