P-gp inhibitor 22
P-gp Inhibitor 22 is a potent small molecule that blocks P-glycoprotein-mediated drug efflux. This action induces S-phase cell cycle arrest and promotes apoptosis in resistant cell lines like MCF-7/ADR, making it a valuable research tool for studying multidrug resistance in cancer models both in vitro and in vivo.
Product Specifications
CAS Number
1226674-74-3
Field of Research
Cell Biology, Neuroscience, Pharmacology & Drug Discovery
Smiles
C (#N) C=1C (C2=C3C (=CC=C2OC1N) C=CC (O) =C3) C4=C (Cl) C=CC=C4
Molecular Formula
C20H13ClN2O2
Molecular Weight
348.78
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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