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Pim-1/2 kinase inhibitor 2

Pim-1/2 kinase inhibitor 2 is a competitive dual kinase inhibitor with IC50 values of 1.31 μM (PIM-1) and 0.67 μM (PIM-2) . It demonstrates potent in vitro anticancer activity against several human cancer cell lines, including leukemia and solid tumors, while exhibiting low cytotoxicity toward normal Wi-38 fibroblasts.

Product Specifications

CAS Number

2918764-16-4

Field of Research

Epigenetics & Chromatin, Pharmacology & Drug Discovery; Cell Biology, Signal Transduction

Smiles

C (#N) C1=C (C=2C (=NC3=C (C2) C=C (Cl) C=C3) N4CCOCC4) C=C (NC1=O) C5=CC (O) =CC=C5

Molecular Formula

C25H19ClN4O3

Molecular Weight

458.9

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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