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PKCTheta-IN-1

PKCTheta-IN-1 (Compound 19) is a highly potent macrocyclic inhibitor of PKCθ, exhibiting an IC50 of 0.1 nM. This inhibitor is a valuable research tool for studying T-cell signaling and immune regulation in both cellular assays and animal models of autoimmune and inflammatory diseases.

Product Specifications

CAS Number

2948289-20-9

Field of Research

Epigenetics & Chromatin, Signal Transduction

Smiles

O=C1N2C=3C (N1) =NC=CC3O[C@H] (C) CCN4C5=NC2=CC=C5C (=O) NC4 (C) C

Molecular Formula

C19H20N6O3

Molecular Weight

380.4

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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