PLK1/BRD4-IN-2
PLK1/BRD4-IN-2 (compound 15) is a dual inhibitor derived from BI-2536, potently targeting both PLK1 (IC50 = 40 nM) and the BRD4 bromodomain (IC50 = 28 nM) . This small molecule is a valuable chemical probe for cancer research, enabling the study of concurrent PLK1 and BRD4 inhibition in cellular and biochemical assays.
Product Specifications
CAS Number
2251709-89-2
Field of Research
Epigenetics & Chromatin
Smiles
C[C@H]1N (C=2C (N (C) C1=O) =CN=C (NC3=C (OC) C=C (C (=O) N4CCCCCC4) C=C3) N2) C5CCCC5
Molecular Formula
C27H36N6O3
Molecular Weight
492.61
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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