PRMT5-IN-32
PRMT5-IN-32 is a potent and selective PRMT5 inhibitor, demonstrating anti-proliferative activity in HCT116 colorectal cancer cells with an IC50 of 0.13 μM. This compound is a valuable chemical probe for investigating PRMT5 biology in cancer research and epigenetic studies, both in vitro and in vivo.
Product Specifications
CAS Number
2918815-34-4
Field of Research
Epigenetics & Chromatin
Smiles
C (N1[C@@]2 (C=3C (C1=O) =CC (F) =CC3) C (=O) N (CC4=C (F) C=C (F) C (F) =C4) CC2) C5=CC=6C (N5) =NC (N) =CC6C
Molecular Formula
C27H21F4N5O2
Molecular Weight
523.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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