PROTAC TYK2 degrader-1
PROTAC TYK2 degrader-1 (CPD-155) is a selective, heterobifunctional degrader that recruits the VHL E3 ligase to induce TYK2 degradation with >60% Dmax. This tool compound enables the investigation of TYK2 biology and its therapeutic potential in autoimmune and inflammatory disease models, both in vitro and in vivo.
Product Specifications
CAS Number
2770470-20-5
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology
Smiles
O=C1C=2C (C (=O) N1C3C (=O) NC (=O) CC3) =CC=CC2NCCCCCNC (=O) C=4C=CC (NC5=CC (NC6=C (OC) C (=CC=C6) C=7N=CN (C) N7) =C (C (NC) =O) N=N5) =NC4
Molecular Formula
C40H41N13O7
Molecular Weight
815.84
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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