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PTK7/β-catenin-IN-2

PTK7/β-catenin-IN-2 (04967) is a dual inhibitor of the PTK7/β-catenin interaction and the p53-MDM2 binding, with IC50 values of 5.6 μM and 157.1 μM, respectively. It disrupts Wnt/β-catenin signaling, supporting its use in anticancer research for inhibiting Wnt-dependent cell proliferation in vitro.

Product Specifications

CAS Number

902434-29-1

Field of Research

Signal Transduction, Stem Cell & Developmental Biology

Smiles

CC=1N2C (=CC (=N2) C3=CC=C (Cl) C=C3) N=C (C) C1CCC (NCCCN4CCN (CC4) C5=CC (Cl) =CC=C5) =O

Molecular Formula

C30H34Cl2N6O

Molecular Weight

565.54

Storage Conditions

-20°C

Notes

For research use only.

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