PTK7/β-catenin-IN-2
PTK7/β-catenin-IN-2 (04967) is a dual inhibitor of the PTK7/β-catenin interaction and the p53-MDM2 binding, with IC50 values of 5.6 μM and 157.1 μM, respectively. It disrupts Wnt/β-catenin signaling, supporting its use in anticancer research for inhibiting Wnt-dependent cell proliferation in vitro.
Product Specifications
CAS Number
902434-29-1
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Smiles
CC=1N2C (=CC (=N2) C3=CC=C (Cl) C=C3) N=C (C) C1CCC (NCCCN4CCN (CC4) C5=CC (Cl) =CC=C5) =O
Molecular Formula
C30H34Cl2N6O
Molecular Weight
565.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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