SHEN26
SHEN26 (ATY014) is an orally bioavailable 5’-cyclohexanecarboxylate derivative of GS-441524, functioning as a potent SARS-CoV-2 RdRp inhibitor (IC50 = 1.36 μM) to block viral RNA replication. It demonstrates antiviral activity in both cellular assays and animal models, supporting its use in COVID-19 therapeutic research.
Product Specifications
CAS Number
2691076-98-7
Field of Research
Infectious Disease & Virology
Smiles
C (#N) [C@]1 (O[C@H] (COC (=O) C2CCCCC2) [C@@H] (O) [C@H]1O) C=3N4C (=CC3) C (N) =NC=N4
Molecular Formula
C19H23N5O5
Molecular Weight
401.42
Storage Conditions
-20°C
Notes
For research use only.
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