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SHEN26

SHEN26 (ATY014) is an orally bioavailable 5’-cyclohexanecarboxylate derivative of GS-441524, functioning as a potent SARS-CoV-2 RdRp inhibitor (IC50 = 1.36 μM) to block viral RNA replication. It demonstrates antiviral activity in both cellular assays and animal models, supporting its use in COVID-19 therapeutic research.

Product Specifications

CAS Number

2691076-98-7

Field of Research

Infectious Disease & Virology

Smiles

C (#N) [C@]1 (O[C@H] (COC (=O) C2CCCCC2) [C@@H] (O) [C@H]1O) C=3N4C (=CC3) C (N) =NC=N4

Molecular Formula

C19H23N5O5

Molecular Weight

401.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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