Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

SIK-IN-2

SIK-IN-2 (Compound 45) is a highly potent, pan-SIK inhibitor with single-digit nanomolar IC50 values against SIK1, SIK2, and SIK3. It modulates macrophage cytokine profiles by potently suppressing TNFα and enhancing LPS-induced IL-10 release, making it a valuable tool for studying SIK signaling in inflammation and immunometabolism in cellular models.

Product Specifications

CAS Number

3033846-20-4

Field of Research

Epigenetics & Chromatin, Signal Transduction

Smiles

C (#N) C=1N2C (=CN=C2C=CC1N) C3=CC (OCC4 (N) CCCC4) =C (C#N) C (SC) =C3

Molecular Formula

C22H22N6OS

Molecular Weight

418.52

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Clobetasone Butyrate EP Impurity I
RM-C150509-01 10 mg

Clobetasone Butyrate EP Impurity I

Sign In for Pricing
View Details
Clobetasone Butyrate EP Impurity I
RM-C150509-02 25 mg

Clobetasone Butyrate EP Impurity I

Sign In for Pricing
View Details
Clobetasone Butyrate EP Impurity I
RM-C150509-03 50 mg

Clobetasone Butyrate EP Impurity I

Sign In for Pricing
View Details
Clobetasone Butyrate EP Impurity I
RM-C150509-04 100 mg

Clobetasone Butyrate EP Impurity I

Sign In for Pricing
View Details
PKC theta, CT (Protein Kinase C theta Type, nPKC-theta, PRKCQ, PRKCT) (Azide free) (HRP) discontinued
P9103-68B-HRP 200 µL

PKC theta, CT (Protein Kinase C theta Type, nPKC-theta, PRKCQ, PRKCT) (Azide free) (HRP) discontinued

Sign In for Pricing
View Details
Boc-O-methyl-L-serine dicyclohexylammonium salt 99+% (TLC)
236633-01 1 g

Boc-O-methyl-L-serine dicyclohexylammonium salt 99+% (TLC)

Sign In for Pricing
View Details