Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

SIK-IN-2

SIK-IN-2 (Compound 45) is a highly potent, pan-SIK inhibitor with single-digit nanomolar IC50 values against SIK1, SIK2, and SIK3. It modulates macrophage cytokine profiles by potently suppressing TNFα and enhancing LPS-induced IL-10 release, making it a valuable tool for studying SIK signaling in inflammation and immunometabolism in cellular models.

Product Specifications

CAS Number

3033846-20-4

Field of Research

Epigenetics & Chromatin, Signal Transduction

Smiles

C (#N) C=1N2C (=CN=C2C=CC1N) C3=CC (OCC4 (N) CCCC4) =C (C#N) C (SC) =C3

Molecular Formula

C22H22N6OS

Molecular Weight

418.52

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

TNNI3K Rabbit Polyclonal Antibody (Biotin)
orb2591937 100 µg

TNNI3K Rabbit Polyclonal Antibody (Biotin)

Sign In for Pricing
View Details
OXA1L Rabbit pAb
E47R17574 100 µL

OXA1L Rabbit pAb

Sign In for Pricing
View Details
CCDC61, NT (CCDC61, Coiled-coil domain-containing protein 61) (Azide free) (HRP) discontinued
033336-HRP 200 µL

CCDC61, NT (CCDC61, Coiled-coil domain-containing protein 61) (Azide free) (HRP) discontinued

Sign In for Pricing
View Details
CHST13 Polyclonal Antibody
orb1414267 100 µL

CHST13 Polyclonal Antibody

Sign In for Pricing
View Details
ATAD3A Rabbit Polyclonal Antibody (Biotin)
orb445755 100 µL

ATAD3A Rabbit Polyclonal Antibody (Biotin)

Sign In for Pricing
View Details
SAFB2 Polyclonal Antibody
MBS2554616-01 0.06 mL

SAFB2 Polyclonal Antibody

Sign In for Pricing
View Details