T-1-PMPA

T-1-PMPA is a potent and apoptosis-inducing EGFR inhibitor, effective against both wild-type (IC50 = 86 nM) and T790M mutant (IC50 = 561.73 nM) EGFR. It is a valuable research tool for in vitro and in vivo studies in oncology, particularly for investigating resistance mechanisms in non-small cell lung cancer models.