T-1-PMPA
T-1-PMPA is a potent and apoptosis-inducing EGFR inhibitor, effective against both wild-type (IC50 = 86 nM) and T790M mutant (IC50 = 561.73 nM) EGFR. It is a valuable research tool for in vitro and in vivo studies in oncology, particularly for investigating resistance mechanisms in non-small cell lung cancer models.
Product Specifications
CAS Number
1323883-62-0
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
O=C1C2=C (N (C) C (=O) N1CC (NC3=CC=C (C) C=C3) =O) N=CN2C
Molecular Formula
C16H17N5O3
Molecular Weight
327.34
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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