VDX-111
VDX-111, a vitamin D analog, induces necroptotic cell death in ovarian cancer cells via RIPK1/RIPK3 pathway activation and cytokine production. It has demonstrated cytotoxic effects in vitro and antitumor efficacy in mouse xenograft models, supporting its use in oncology research focused on programmed necrosis.
Product Specifications
CAS Number
158983-23-4
Field of Research
Cell Biology, Signal Transduction
Smiles
C[C@@]12[C@] (\C (=C\C=C/3\C[C@@H] (OC (CBr) =O) C[C@H] (O) C3=C) \CCC1) (CC[C@@]2 ([C@@H] (CCCC (C) (C) O) C) [H]) [H]
Molecular Formula
C29H45BrO4
Molecular Weight
537.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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