PROTAC SOS1 degrader-8
PROTA CSOS1 degrader-8 (Compd 1) is a SOS1-targeting PROTAC molecule. It facilitates the ubiquitination and degradation of SOS1, a key RAS activator, and is utilized in vitro and in vivo for investigating KRAS-driven cancer biology and targeted protein degradation strategies.
Product Specifications
CAS Number
3036155-11-7
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
N ([C@H] (C) C1=C (C) C (C#N) =CC=C1) C=2C3=C (C=NC (=C3) N4CCN (C (=O) C5CCN (CC6CCC7 (CC6) CCN (C (=O) C8=CC (=C (Cl) C=C8) N9C (=O) NC (=O) CC9) CC7) CC5) CC4) C (C) =NN2
Molecular Formula
C50H60ClN11O4
Molecular Weight
914.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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