RG7112D
RG7112D is a potent and selective MDM2 inhibitor (IC50=11 nM) that stabilizes p53 and is used as a warhead in PROTACs like YX-02-030. It is a valuable chemical tool for cancer research, enabling the study of p53 reactivation pathways in both cellular and in vivo models.
Product Specifications
CAS Number
2360561-90-4
Field of Research
Cell Biology
Smiles
C[C@@]1 (N (C (=O) N2CCN (CC (O) =O) CC2) C (=N[C@@]1 (C) C3=CC=C (Cl) C=C3) C4=C (OCC) C=C (C (C) (C) C) C=C4) C5=CC=C (Cl) C=C5
Molecular Formula
C36H42Cl2N4O4
Molecular Weight
665.65
Storage Conditions
-20°C
Notes
For research use only.
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