3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles
This small molecule is a dual inhibitor of BMP2 (IC50 = 2.2 μM) and MEK1. It has demonstrated anti-inflammatory and neuroprotective activity in the EAE mouse model, supporting its use in research on neuroinflammation, bone biology, and MAPK/MEK signaling pathways.
Product Specifications
CAS Number
287196-91-2
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Smiles
N#CC=1C (=O) NSC1NC=2C=CC=CC2C (F) (F) F
Molecular Formula
C11H6F3N3OS
Molecular Weight
285.25
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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