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DBCO-β-Glu-PEG12-Exatecan

DBCO-β-Glu-PEG12-Exatecan is a drug-linker conjugate featuring the topoisomerase I inhibitor Exatecan. It is designed for constructing antibody-drug conjugates (ADCs) and is suitable for both in vitro biochemical assays and in vivo efficacy studies in cancer research.

Product Specifications

CAS Number

3025107-83-6

Field of Research

Molecular Biology, Pharmacology & Drug Discovery

Smiles

N (C (OCC1=CC (CNC (CCNC ([C@@H] (NC (CCCCC (=O) N2C=3C (C#CC=4C (C2) =CC=CC4) =CC=CC3) =O) CNC (CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC) =O) =O) =O) =C (O[C@@H]5O[C@H] (C (O) =O) [C@@H] (O) [C@H] (O) [C@H]5O) C=C1) =O) [C@@H]6C7=C8C (C=9N (C8) C (=O) C%10=C (C9) [C@] (CC) (O) C (=O) OC%10) =NC=%11C7=C (CC6) C (C) =C (F) C%11

Molecular Formula

C92H117FN8O30

Molecular Weight

1833.95

Storage Conditions

-20°C

Notes

For research use only.

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