PROTAC HPK1 Degrader-2
PROTACHPK1 Degrader-2 (compound 3) is a potent and selective HPK1 degrader with a DC50 of 23 nM in human PBMCs. This small molecule PROTAC is a valuable chemical tool for investigating HPK1 biology and its role in immuno-oncology, supporting both in vitro and in vivo research applications.
Product Specifications
CAS Number
2893885-31-7
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
O=C1NC (=O) CCN1C2=CC=C (C=C2) N3CCN (C (=O) CCN4CC5=C (C=C (C=C5CC4) C6=NC7=C (N=C6) NC=C7C=8C=CC (C (=O) N (C) C) =C (C8) C) C) CC3
Molecular Formula
C43H47N9O4
Molecular Weight
753.89
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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