(R) -JAK2/STAT3-IN-10a
(R) -JAK2/STAT3-IN-10a is the R-enantiomer of the GP130 D1 domain inhibitor JAK2/STAT3-IN-1, exhibiting a KD of 3.8 μM for GP130. It suppresses JAK2 and STAT3 phosphorylation, demonstrating antitumor activity in cellular assays and providing a research tool for studying cytokine signaling in oncology.
Product Specifications
CAS Number
2485758-49-2
Product Name Alternative
(R) JAK2/STAT3IN1, antiviral
Field of Research
Cancer Biology; Epigenetics & Chromatin, Cell Biology, Immunology & Inflammation
Purity
97.99% (May vary between batches)
Smiles
C (N) (=O) N1[C@@H] (C=2C=3C (N (CC4=CC=C (OCCN5CCCCCC5) C=C4) C2) =CC=C (Br) C3) CC (=N1) C6=CC=C (C (F) (F) F) C=C6
Molecular Formula
C34H35BrF3N5O2
Molecular Weight
682.57
Storage Conditions
-20°C
Notes
For research use only.
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