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5'-ODMT cEt m5U Phosphoramidite (Amidite)

This phosphoramidite reagent, featuring a constrained ethyl (cEt) locked nucleic acid (LNA) backbone and a 5-methyluridine (m5U) base, is designed for oligonucleotide synthesis. Its resulting antisense oligonucleotides demonstrate potent gene silencing activity and a favorable safety profile in both cellular and animal studies, supporting therapeutic discovery research.

Product Specifications

CAS Number

1197033-22-9

Field of Research

Cell Biology, Molecular Biology

Smiles

[H][C@]12O[C@@H] (C) [C@] (COC (c3ccccc3) (c3ccc (OC) cc3) c3ccc (OC) cc3) (O[C@H]1n1cc (C) c (=O) [nH]c1=O) [C@H]2OP (OCCC#N) N (C (C) C) C (C) C

Molecular Formula

C42H51N4O9P

Molecular Weight

786.85

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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