Triamterene
Triamterene is a pressure-sensitive ENaC blocker used as a diuretic agent. It also functions as a TGR5 receptor antagonist, inhibiting TGR5-mediated GLP-1 secretion and cAMP elevation. This small molecule is applied in research on hypertension, fluid balance, and metabolic pathways in both cellular and animal models.
Product Specifications
CAS Number
396-01-0
Product Name Alternative
Ademine, G-protein coupled receptor 19, G protein-coupled Bile Acid Receptor 1, GPBAR1, GPCR19, ENaC, ENaCαS583, Inhibitor, inhibit, Na channels, Na+ channels, SodiumChannel, Sodium Channel, SKF8542, SKF-8542, SKF 8542, Triamterene, TGR5
Field of Research
Pharmacology & Drug Discovery
Purity
99.49% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.95 mM) ; DMSO:3.33 mg/mL (13.15 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
Nc1nc (N) c2nc (c (N) nc2n1) -c1ccccc1
Molecular Formula
C12H11N7
Molecular Weight
253.26
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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