YS-67
YS-67 is a potent, selective, and orally bioavailable EGFR inhibitor. It demonstrates antitumor activity by suppressing p-EGFR and p-AKT, inhibiting proliferation and inducing G0/G1 phase cell cycle arrest and apoptosis in cells like A549, PC-9, and A431, supporting its research use in non-small-cell lung cancer.
Product Specifications
CAS Number
2761327-15-3
Product Name Alternative
YS67, EGFR, Apoptosis, Akt
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
98.88% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.91 mM) ; DMSO:10 mg/mL (19.13 mM)
Smiles
N=1C=NC (=C2C=C (OCCCN3CCOCC3) C (OC) =CC12) C=4C=5C=CC=CC5N (C4C=6C=CC=CC6) CC
Molecular Formula
C32H34N4O3
Molecular Weight
522.64
Storage Conditions
-20°C
Notes
For research use only.
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