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VU0453379

VU0453379 is a brain-penetrant, selective positive allosteric modulator of the GLP-1 receptor with an EC50 of 1.3 μM. It is a valuable research tool for investigating central GLP-1R signaling in models of metabolic and neurodegenerative diseases, applicable in both in vitro and in vivo studies.

Product Specifications

CAS Number

1638646-27-1

Field of Research

Pharmacology & Drug Discovery

Smiles

C (NC[C@H]1N (C (C) C) CCC1) (=O) C=2C3=C (N (C) C=4C3=CC=CC4) C (=O) N (C2) C5CCCC5

Molecular Formula

C26H34N4O2

Molecular Weight

434.57

Storage Conditions

-20°C

Notes

For research use only.

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