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(S, R, S) -AHPC-PEG5-COOH

(S, R, S) -AHPC-PEG5-COOH (VH032-PEG5-COOH) is a VHL E3 ligase ligand conjugated to a flexible pentameric polyethylene glycol linker. This synthetic compound is a key building block for constructing PROTAC degraders, enabling targeted protein degradation research in both cellular and in vivo models.

Product Specifications

CAS Number

2172820-14-1

Field of Research

Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Smiles

Cc1ncsc1-c1ccc (CNC (=O) [C@@H]2C[C@@H] (O) CN2C (=O) [C@@H] (NC (=O) CCOCCOCCOCCOCCOCCC (O) =O) C (C) (C) C) cc1

Molecular Formula

C36H54N4O11S

Molecular Weight

750.9

Storage Conditions

-20°C

Notes

For research use only.

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