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Anticancer agent 136

Compound 22 is a triazole-modified geldanamycin analog that binds Hsp90 with a Kd of 3.86 μM. It demonstrates cytotoxic activity with an IC50 of 3.38 μM in HDF cells, inducing apoptosis. This small molecule is a useful research tool for studying Hsp90 inhibition in cancer biology and apoptosis mechanisms in vitro.

Product Specifications

Field of Research

Cell Biology

Molecular Formula

C40H50N6O8

Molecular Weight

742.86

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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