Anticancer agent 136
Compound 22 is a triazole-modified geldanamycin analog that binds Hsp90 with a Kd of 3.86 μM. It demonstrates cytotoxic activity with an IC50 of 3.38 μM in HDF cells, inducing apoptosis. This small molecule is a useful research tool for studying Hsp90 inhibition in cancer biology and apoptosis mechanisms in vitro.
Product Specifications
Field of Research
Cell Biology
Molecular Formula
C40H50N6O8
Molecular Weight
742.86
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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