Akt/NF-κB/MAPK-IN-1

Akt/NF-κB/MAPK-IN-1 is a potent, orally bioavailable small molecule inhibitor of nitric oxide production (IC50 = 7.70 μM) . It exhibits anti-inflammatory activity in research settings by suppressing the Akt/NF-κB and MAPK signaling pathways, demonstrating utility for both in vitro and in vivo pharmacological studies.